Royal Air Force Typhoon jets have conducted a mission with French warplanes in a combined operation targeting an hidden munitions depot in Syria used by the IS group, as stated by the UK's MoD.
The site, located using surveillance, was thought to be storing arms and explosives, the statement said, and was located in mountainous terrain just north of Palmyra in Syria's central region.
"Our fighter planes employed precision-guided Paveway IV munitions to hit a series of access tunnels leading to the site... early reports are that the objective was successfully hit," officials stated.
There was no sign of any harm to civilians in the strike conducted Saturday night and every plane involved returned safely, the defence officials confirmed.
The British jets were assisted by a Voyager refuelling tanker.
Daesh - alternatively referred to as Daesh - established jihadist rule over significant areas in both Syria and Iraq until 2019.
"This strike demonstrates our UK leadership, and commitment to operate in unison with our partners, to stamp out any revival of Daesh and their violent and radical beliefs in the Middle East," the British Defence Secretary John Healey said.
RAF aircraft have performed surveillance missions over Syria to "forestall any attempted resurgence" of the group subsequent to its defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I want to thank all the members of the UK armed forces involved in this operation for their expertise and their bravery," the Defence Secretary added. "They were among a great many British personnel deployed over the festive period. This operation, to eliminate dangerous terrorists who pose a risk to our way of life, demonstrates how UK forces are always on standby, all year round, protecting the UK within its borders and strong abroad."
In December, the United States armed forces executed what it termed a "major assault" targeting IS targets in Syria, after an ambush resulted in the deaths of two American soldiers and a local interpreter in the Palmyra area.
The U.N. estimates Islamic State still has an estimated 5,000 to 7,000 militants in both countries.